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Exact Sciences vs Natera: Which Stock Looks Stronger in 2026?

The structural profiles are close, with Natera carrying a narrow edge on growth. Exact Sciences still leads on profitability and valuation, which keeps the comparison from looking entirely one-sided. In the market, Exact Sciences carries the stronger setup — intact trend against Natera's broken trend. That leaves a split case: the structural lead stays with Natera, but the market is not currently confirming it.

The comparison is based on similar long-term financial trajectories, not sector labels. Both peer scores are relative to the Russell 1000 universe, making them directly comparable.

Updated 2026-05-17

The comparison is mainly decided in growth, with the rest of the profile carrying less weight.

INDUSTRY COMPARISON

Both operate in: Diagnostics & Research

This comparison is based on industry proximity, not on functional trajectory similarity. EXAS and NTRA share the same industry classification.

For a similarity-based comparison, see how Exact Sciences and Natera each position within their functional peer groups in AssetNext.

Peer-Relative Score
EXAS
Exact Sciences Corp
45
Peer-Score
Signal qualitylow
Peer basis: Russell 1000
vs
NTRA
Natera, Inc.
46
Peer-Score
Signal qualitylow
Peer basis: Russell 1000

Scores reflect position relative to comparable companies with similar long-term financial trajectories.

The clearest separation appears in growth.

Dimension spread: EXAS vs NTRA Profitability 43 25 Stability 62 67 Valuation 43 30 Growth 36 81 EXAS NTRA
Gap Ranking
#1 Growth +45
#2 Profitability +18
#3 Valuation +13
#4 Stability +5
Price Setup

Left means cheaper relative valuation. Higher means stronger structure.

Price setup map for EXAS and NTRA Stronger + cheaper Stronger + richer Weaker + cheaper Weaker + richer EXASNTRA Relative valuation Structural strength

Natera, Inc. looks stronger on relative valuation, while the broader price setup remains mixed.

Valuation position uses Forward P/E and peer-relative valuation score where available.

Entry today — historical context

Where EXAS and NTRA each sit in their own 4.9-year price and valuation history.

BASED ON 4.9-YEAR HISTORY EXAS Elevated · above norm 0th 50th 100th 6 pct gap NTRA Elevated · near norm 0th 50th 100th 95th 89th
EXAS (95th percentile) and NTRA (89th percentile) both sit in the upper portion of their own 5-year ranges. The historical entry context is broadly similar for both. This reflects entry timing, not which company is structurally stronger.

Describes historical entry positioning only. Descriptive — not investment advice.

Relative Position vs Comparable Companies
Growth
On growth, Natera, Inc. ranks near the top of the group; Exact Sciences Corp sits in the weaker half.
Profitability
Exact Sciences Corp holds the stronger peer position on profitability.
Growth — Dominant Gap
EXAS
36
NTRA
81
Gap+45in favour of NTRA

The current lead is backed by a stronger multi-year growth trajectory.

What keeps the gap from being one-sided

Capital efficiency also runs the other way, with a 18.2-point ROIC edge acting as a real counterforce.

What this means for the comparison

The main read on growth is clearer than the broader score gap.

Explore full peer positioning in AssetNext

Break down the EXAS vs NTRA comparison across all dimensions with the full interactive tool.

Explore full breakdown →
Similar growth-driven comparisons

Explore how EXAS and NTRA each compare against other companies in their peer groups.

Rule-based, descriptive analysis only. Derived from peer percentile dimensions. Not investment advice. Peer groups are determined algorithmically based on structural similarity — not by sector classification alone.

How AssetNext Peer Scores Work

AssetNext scores reflect each company's structural position within its functional peer group — not a ranking against all stocks simultaneously. Peers are identified by similarity across eight financial dimensions, including revenue growth trajectory, margin structure, capital intensity, and earnings stability. A score of 75 means the company ranks in the top quartile within its own peer group, not the entire market.

Four dimension scores drive the overall peer score: Growth (revenue trajectory and expansion dynamics), Quality (margin structure and capital efficiency), Valuation (peer-relative pricing on standard multiples), and Stability (earnings consistency and financial predictability). Each dimension is scored 0–100 relative to the peer group, then combined into an overall peer score using equal weighting.

Because scores are peer-relative, the same company can have slightly different scores in different index universes. On comparison pages, both companies are shown within their shared peer universe wherever possible — so the scores are directly comparable. The peer basis is stated on each score card.

Scores are recalculated periodically as underlying financial data is updated. All analysis is descriptive and rule-based — AssetNext describes structural realities and never issues buy, sell or hold recommendations.