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Stock Comparison · Industry comparison · Drug Manufacturers - General

AstraZeneca vs Sanofi: Which Stock Looks Stronger in 2026?

AstraZeneca holds the cleaner structural position, with profitability as the main driver and valuation adding further support. Sanofi still has the edge on valuation, which keeps the comparison from looking entirely one-sided. On the market side, AstraZeneca is in better shape — its trend is intact while Sanofi's trend has broken down. That puts structure and market broadly in agreement — AstraZeneca's lead looks more confirmed than conflicted.

The comparison is based on similar long-term financial trajectories, not sector labels. Both peer scores are relative to the STOXX 600 universe, making them directly comparable.

Updated 2026-07-05

The lead is spread across profitability and growth, rather than sitting in one isolated gap. The overall score gap is 8 points in favour of AstraZeneca PLC.

INDUSTRY COMPARISON

Both operate in: Drug Manufacturers - General

This comparison is based on industry proximity, not on functional trajectory similarity. AZN.L and SAN.PA share the same industry classification.

For a similarity-based comparison, see how AstraZeneca and Sanofi each position within their functional peer groups in AssetNext.

Peer-Relative Score
AZN.L
AstraZeneca PLC
50
Peer-Score
Signal qualityHigh
Peer basis: STOXX 600
vs
SAN.PA
Sanofi
42
Peer-Score
Signal qualityHigh
Peer basis: STOXX 600

Scores reflect position relative to comparable companies with similar long-term financial trajectories.

The largest gaps do not all point in the same direction.

Dimension spread: AZN.L vs SAN.PA Profitability 44 11 Stability 68 61 Valuation 43 67 Growth 50 33 AZN.L SAN.PA
Gap Ranking
#1 Profitability +33
#2 Valuation +24
#3 Growth +17
#4 Stability +7
Price Setup

Left means cheaper relative valuation. Higher means stronger structure.

Price setup map for AZN.L and SAN.PA Stronger + cheaper Stronger + richer Weaker + cheaper Weaker + richer AZN.LSAN.PA Relative valuation Structural strength

AstraZeneca PLC looks stronger, but the price setup still looks more supportive for Sanofi.

Valuation position uses peer-relative PE percentile (idx_pct_pe) where available.

Relative Position vs Comparable Companies
Profitability
AstraZeneca PLC holds the stronger peer position on profitability.
Valuation
Both rank well on valuation, but Sanofi still holds a clear edge.
Profitability — Dominant Gap
AZN.L
44
SAN.PA
11
Gap+33in favour of AZN.L

The profitability lead is mainly driven by a 7.9-point operating margin advantage.

What keeps the gap from being one-sided

Absolute pricing still looks more supportive for Sanofi, with a forward P/E that is 8.3 turns lower there.

What this means for the comparison

The profitability lead is clear, but pricing and valuation still pull in the other direction — the result holds, but not without friction.

Explore full peer positioning in AssetNext

Break down the AZN.L vs SAN.PA comparison across all dimensions with the full interactive tool.

Explore full breakdown →
Other comparisons with conflicting dimension signals

Explore how AZN.L and SAN.PA each compare against other companies in their peer groups.

Rule-based, descriptive analysis only. Derived from peer percentile dimensions. Not investment advice. Peer groups are determined algorithmically based on structural similarity — not by sector classification alone.

How AssetNext Peer Scores Work

AssetNext scores reflect each company's structural position within its functional peer group — not a ranking against all stocks simultaneously. Peers are identified by similarity across eight financial dimensions, including revenue growth trajectory, margin structure, capital intensity, and earnings stability. A score of 75 means the company ranks in the top quartile within its own peer group, not the entire market.

Four dimension scores drive the overall peer score: Growth (revenue trajectory and expansion dynamics), Quality (margin structure and capital efficiency), Valuation (peer-relative pricing on standard multiples), and Stability (earnings consistency and financial predictability). Each dimension is scored 0–100 relative to the peer group, then combined into an overall peer score using equal weighting.

Because scores are peer-relative, the same company can have slightly different scores in different index universes. On comparison pages, both companies are shown within their shared peer universe wherever possible — so the scores are directly comparable. The peer basis is stated on each score card.

Scores are recalculated periodically as underlying financial data is updated. All analysis is descriptive and rule-based — AssetNext describes structural realities and never issues buy, sell or hold recommendations.