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Stock Comparison · Industry comparison · Drug Manufacturers - General

AstraZeneca vs Roche Holding: Which Stock Looks Stronger in 2026?

Roche holds the cleaner structural position, with profitability as the main driver and valuation adding further support. AstraZeneca does not offset that deficit through any equally strong structural edge elsewhere. The market setup is broadly comparable for both — no clear directional signal from price behavior. The market is not adding a decisive signal either way — the structural read carries the weight.

The comparison is based on similar long-term financial trajectories, not sector labels. Both peer scores are relative to the STOXX 600 universe, making them directly comparable.

Updated 2026-07-05

The lead is spread across profitability and valuation, rather than sitting in one isolated gap. The overall score gap is 20 points in favour of Roche Holding AG.

INDUSTRY COMPARISON

Both operate in: Drug Manufacturers - General

This comparison is based on industry proximity, not on functional trajectory similarity. AZN.L and ROP.SW share the same industry classification.

For a similarity-based comparison, see how AstraZeneca and Roche each position within their functional peer groups in AssetNext.

Peer-Relative Score
AZN.L
AstraZeneca PLC
50
Peer-Score
Signal qualityHigh
Peer basis: STOXX 600
vs
ROP.SW
Roche Holding AG
70
Peer-Score
Signal qualitylow
Peer basis: STOXX 600

Scores reflect position relative to comparable companies with similar long-term financial trajectories.

The largest gaps do not all point in the same direction.

Dimension spread: AZN.L vs ROP.SW Profitability 44 85 Stability 68 68 Valuation 43 62 Growth 50 61 AZN.L ROP.SW
Gap Ranking
#1 Profitability +41
#2 Valuation +19
#3 Growth +11
#4 Stability
Price Setup

Left means cheaper relative valuation. Higher means stronger structure.

Price setup map for AZN.L and ROP.SW Stronger + cheaper Stronger + richer Weaker + cheaper Weaker + richer AZN.LROP.SW Relative valuation Structural strength

Roche Holding AG looks stronger both structurally and on relative valuation.

Valuation position uses peer-relative PE percentile (idx_pct_pe) where available.

Relative Position vs Comparable Companies
Profitability
Both profiles are strong on profitability, but Roche Holding AG leads clearly.
Valuation
On valuation, the edge still sits with Roche Holding AG, even though both profiles look solid.
Profitability — Dominant Gap
AZN.L
44
ROP.SW
85
Gap+41in favour of ROP.SW

Capital efficiency adds support, with a 13.1-point ROIC advantage.

What keeps the gap from being one-sided

Stability is the one area where AstraZeneca PLC still pushes back materially — it is the steadier name on this dimension, which keeps the result from reading as one-way.

What this means for the comparison

Profitability is the clearest driver, and valuation also supports Roche Holding AG's broader structural position.

Explore full peer positioning in AssetNext

Break down the AZN.L vs ROP.SW comparison across all dimensions with the full interactive tool.

Explore full breakdown →
Similar profitability-driven comparisons

Explore how AZN.L and ROP.SW each compare against other companies in their peer groups.

Rule-based, descriptive analysis only. Derived from peer percentile dimensions. Not investment advice. Peer groups are determined algorithmically based on structural similarity — not by sector classification alone.

How AssetNext Peer Scores Work

AssetNext scores reflect each company's structural position within its functional peer group — not a ranking against all stocks simultaneously. Peers are identified by similarity across eight financial dimensions, including revenue growth trajectory, margin structure, capital intensity, and earnings stability. A score of 75 means the company ranks in the top quartile within its own peer group, not the entire market.

Four dimension scores drive the overall peer score: Growth (revenue trajectory and expansion dynamics), Quality (margin structure and capital efficiency), Valuation (peer-relative pricing on standard multiples), and Stability (earnings consistency and financial predictability). Each dimension is scored 0–100 relative to the peer group, then combined into an overall peer score using equal weighting.

Because scores are peer-relative, the same company can have slightly different scores in different index universes. On comparison pages, both companies are shown within their shared peer universe wherever possible — so the scores are directly comparable. The peer basis is stated on each score card.

Scores are recalculated periodically as underlying financial data is updated. All analysis is descriptive and rule-based — AssetNext describes structural realities and never issues buy, sell or hold recommendations.