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Stock Comparison · Structural lead, mixed market

Alnylam Pharmaceuticals vs Shopify: Which Stock Looks Stronger in 2026?

Alnylam Pharmaceuticals holds the cleaner structural position, with the lead spread across stability and valuation. Shopify does not offset that deficit through any equally strong structural edge elsewhere. The market setup is currently leaning toward Shopify, which does not confirm the structural lead. That leaves a split case: the structural lead stays with Alnylam Pharmaceuticals, but the market is not currently confirming it.

The comparison is based on similar long-term financial trajectories, not sector labels. Both peer scores are relative to the Nasdaq 100 universe, making them directly comparable.

Updated 2026-08-16

The clearest separation starts in stability, but valuation adds another real layer to the result. The overall score gap is 24 points in favour of Alnylam Pharmaceuticals, Inc..

Trajectory Similarity
0.68
Moderately similar
Peer-set rank: #11
within Alnylam Pharmaceuticals, Inc.'s functional peer set

This comparison is anchored in long-term financial trajectory similarity within the selected peer universe.

The pair shares a valid long-term profile match, but the trajectories are not especially close.

Most of the shared profile comes through investment intensity and revenue growth trajectory.

Similarity drivers
investment intensityrevenue growth trajectory
What reduces the match
margin trend
How to read the score
0.85–1.00 · Very similar0.70–0.84 · Similar0.55–0.69 · Moderately similarbelow 0.55 · Loose match
Peer-Relative Score
ALNY
Alnylam Pharmaceuticals, Inc.
70
Peer-Score
Signal qualitylow
Peer basis: Nasdaq 100
vs
SHOP
Shopify Inc.
46
Peer-Score
Signal qualitylow
Peer basis: Nasdaq 100

Scores reflect position relative to comparable companies with similar long-term financial trajectories.

The largest gaps do not all point in the same direction.

Dimension spread: ALNY vs SHOP Profitability 75 64 Stability 68 28 Valuation 62 26 Growth 77 66 ALNY SHOP
Gap Ranking
#1 Stability +40
#2 Valuation +36
#3 Growth +11
#4 Profitability +11
Price Setup

Left means cheaper relative valuation. Higher means stronger structure.

Price setup map for ALNY and SHOP Stronger + cheaper Stronger + richer Weaker + cheaper Weaker + richer ALNYSHOP Relative valuation Structural strength

Alnylam Pharmaceuticals, Inc. looks stronger on relative valuation, while the broader price setup remains mixed.

Valuation position uses peer-relative PE percentile (idx_pct_pe) where available.

Entry today — historical context

Where ALNY and SHOP each sit in their own 5-year price and valuation history.

BASED ON 5-YEAR HISTORY ALNY Neutral · below norm 0th 50th 100th 40 pct gap SHOP Elevated · above norm 0th 50th 100th 54th 94th
Today ALNY sits in the upper-middle of its own 5-year history (54th percentile), while SHOP sits higher in its own history (94th). Within each stock's own 5-year context, ALNY is at a historically more favourable entry position than SHOP. This reflects entry timing, not which company is structurally stronger — peer-relative analysis is a separate question addressed above.

Describes historical entry positioning only. Descriptive — not investment advice.

Relative Position vs Comparable Companies
Stability
On stability, Alnylam Pharmaceuticals, Inc. ranks near the top of the group; Shopify Inc. sits in the weaker half.
Valuation
Alnylam Pharmaceuticals, Inc. sits in the stronger part of the group on valuation, while Shopify Inc. is closer to mid-pack.
Stability — Dominant Gap
ALNY
68
SHOP
28
Gap+40in favour of ALNY

The stability gap is very wide, with the stronger side looking materially steadier through time.

What keeps the gap from being one-sided

Shopify Inc. still carries lower volatility exposure — that difference is real enough to prevent the comparison from becoming one-sided.

What this means for the comparison

The lead is built on both stability and valuation, making it broader than a single-dimension result.

Explore full peer positioning in AssetNext

Break down the ALNY vs SHOP comparison across all dimensions with the full interactive tool.

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Similar stability-and-valuation comparisons

Explore how ALNY and SHOP each compare against other companies in their peer groups.

Rule-based, descriptive analysis only. Derived from peer percentile dimensions. Not investment advice. Peer groups are determined algorithmically based on structural similarity — not by sector classification alone.

How AssetNext Peer Scores Work

AssetNext scores reflect each company's structural position within its functional peer group — not a ranking against all stocks simultaneously. Peers are identified by similarity across eight financial dimensions, including revenue growth trajectory, margin structure, capital intensity, and earnings stability. A score of 75 means the company ranks in the top quartile within its own peer group, not the entire market.

Four dimension scores drive the overall peer score: Growth (revenue trajectory and expansion dynamics), Quality (margin structure and capital efficiency), Valuation (peer-relative pricing on standard multiples), and Stability (earnings consistency and financial predictability). Each dimension is scored 0–100 relative to the peer group, then combined into an overall peer score using equal weighting.

Because scores are peer-relative, the same company can have slightly different scores in different index universes. On comparison pages, both companies are shown within their shared peer universe wherever possible — so the scores are directly comparable. The peer basis is stated on each score card.

Scores are recalculated periodically as underlying financial data is updated. All analysis is descriptive and rule-based — AssetNext describes structural realities and never issues buy, sell or hold recommendations.