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Stock Comparison · Structural lead, mixed market

Alnylam Pharmaceuticals vs Natera: Which Stock Looks Stronger in 2026?

Alnylam Pharmaceuticals holds the cleaner structural position, with profitability as the main driver and growth adding further support. Natera does not offset that deficit through any equally strong structural edge elsewhere. In the market, Natera carries the stronger setup — intact trend against Alnylam Pharmaceuticals's broken trend. That leaves a split case: the structural lead stays with Alnylam Pharmaceuticals, but the market is not currently confirming it.

The comparison is based on similar long-term financial trajectories, not sector labels. Both peer scores are relative to the Russell 1000 universe, making them directly comparable.

Updated 2026-07-05

Profitability still does most of the heavy lifting in this comparison. The overall score gap is 15 points in favour of Alnylam Pharmaceuticals, Inc..

Trajectory Similarity
0.76
Similar
Peer-set rank: #2
within Alnylam Pharmaceuticals, Inc.'s functional peer set

This pair is matched through long-term financial trajectory similarity within the selected peer universe.

This level of similarity signals a strong structural match, even though some dimensions still separate the two companies.

The match is driven mainly by investment intensity and revenue growth trajectory.

Similarity drivers
investment intensityrevenue growth trajectory
What reduces the match
margin trend
How to read the score
0.85–1.00 · Very similar0.70–0.84 · Similar0.55–0.69 · Moderately similarbelow 0.55 · Loose match
Peer-Relative Score
ALNY
Alnylam Pharmaceuticals, Inc.
61
Peer-Score
Signal qualitylow
Peer basis: Russell 1000
vs
NTRA
Natera, Inc.
46
Peer-Score
Signal qualitylow
Peer basis: Russell 1000

Scores reflect position relative to comparable companies with similar long-term financial trajectories.

The largest gaps do not all point in the same direction.

Dimension spread: ALNY vs NTRA Profitability 66 23 Stability 70 73 Valuation 32 30 Growth 88 78 ALNY NTRA
Gap Ranking
#1 Profitability +43
#2 Growth +10
#3 Stability +3
#4 Valuation +2
Price Setup

Left means cheaper relative valuation. Higher means stronger structure.

Price setup map for ALNY and NTRA Stronger + cheaper Stronger + richer Weaker + cheaper Weaker + richer ALNYNTRA Relative valuation Structural strength

Alnylam Pharmaceuticals, Inc. is stronger, but the price setup still looks more supportive for Natera, Inc..

Valuation position uses peer-relative PE percentile (idx_pct_pe) and peer-relative valuation score where available.

Entry today — historical context

Where ALNY and NTRA each sit in their own 5-year price and valuation history.

BASED ON 5-YEAR HISTORY ALNY Elevated · near norm 0th 50th 100th 15 pct gap NTRA Elevated · above norm 0th 50th 100th 84th 99th
ALNY (84th percentile) and NTRA (99th percentile) both sit in the upper portion of their own 5-year ranges. The historical entry context is broadly similar for both. This reflects entry timing, not which company is structurally stronger.

Describes historical entry positioning only. Descriptive — not investment advice.

Relative Position vs Comparable Companies
Profitability
On profitability, Alnylam Pharmaceuticals, Inc. ranks near the top of the group; Natera, Inc. sits in the weaker half.
Growth
On growth, the same pattern holds: both rank well, but Alnylam Pharmaceuticals, Inc. still sits higher.
Profitability — Dominant Gap
ALNY
66
NTRA
23
Gap+43in favour of ALNY

The profitability lead is mainly driven by a 35-point operating margin advantage.

What keeps the gap from being one-sided

On the market side, Natera carries the stronger trend while Alnylam Pharmaceuticals's trend has broken — the market setup does not confirm the structural advantage.

What this means for the comparison

Profitability is the clearest driver, and growth also supports Alnylam Pharmaceuticals, Inc.'s broader structural position.

Explore full peer positioning in AssetNext

Break down the ALNY vs NTRA comparison across all dimensions with the full interactive tool.

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Similar profitability-driven comparisons

Explore how ALNY and NTRA each compare against other companies in their peer groups.

Rule-based, descriptive analysis only. Derived from peer percentile dimensions. Not investment advice. Peer groups are determined algorithmically based on structural similarity — not by sector classification alone.

How AssetNext Peer Scores Work

AssetNext scores reflect each company's structural position within its functional peer group — not a ranking against all stocks simultaneously. Peers are identified by similarity across eight financial dimensions, including revenue growth trajectory, margin structure, capital intensity, and earnings stability. A score of 75 means the company ranks in the top quartile within its own peer group, not the entire market.

Four dimension scores drive the overall peer score: Growth (revenue trajectory and expansion dynamics), Quality (margin structure and capital efficiency), Valuation (peer-relative pricing on standard multiples), and Stability (earnings consistency and financial predictability). Each dimension is scored 0–100 relative to the peer group, then combined into an overall peer score using equal weighting.

Because scores are peer-relative, the same company can have slightly different scores in different index universes. On comparison pages, both companies are shown within their shared peer universe wherever possible — so the scores are directly comparable. The peer basis is stated on each score card.

Scores are recalculated periodically as underlying financial data is updated. All analysis is descriptive and rule-based — AssetNext describes structural realities and never issues buy, sell or hold recommendations.