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Stock Comparison · Structural lead, mixed market

Alnylam Pharmaceuticals vs Natera: Which Stock Looks Stronger in 2026?

Alnylam Pharmaceuticals holds the cleaner structural position, with profitability as the main driver and valuation adding further support. Natera still has the edge on valuation, which keeps the comparison from looking entirely one-sided. In the market, Natera carries the stronger setup — intact trend against Alnylam Pharmaceuticals's broken trend. That leaves a split case: the structural lead stays with Alnylam Pharmaceuticals, but the market is not currently confirming it.

The comparison is based on similar long-term financial trajectories, not sector labels.

Updated 2026-04-05

Most of the separation is still concentrated in profitability. The overall score gap is 17 points in favour of Alnylam Pharmaceuticals, Inc..

Trajectory Similarity
0.75
Similar
Peer-set rank: #2
within Alnylam Pharmaceuticals, Inc.'s functional peer set

This pair is matched through long-term financial trajectory similarity within the selected peer universe.

This level of similarity signals a strong structural match, even though some dimensions still separate the two companies.

The match is driven mainly by investment intensity and revenue growth trajectory.

Similarity drivers
investment intensityrevenue growth trajectory
What reduces the match
margin trend
How to read the score
0.85–1.00 · Very similar0.70–0.84 · Similar0.55–0.69 · Moderately similarbelow 0.55 · Loose match
Peer-Relative Score
ALNY
Alnylam Pharmaceuticals, Inc.
56
Peer-Score
Signal qualityHigh
vs
NTRA
Natera, Inc.
39
Peer-Score
Signal qualityHigh

Scores reflect position relative to comparable companies with similar long-term financial trajectories.

The largest gaps do not all point in the same direction.

Dimension spread: ALNY vs NTRA Profitability 78 5 Stability 53 43 Valuation 14 30 Growth 91 100 ALNY NTRA
Gap Ranking
#1 Profitability +73
#2 Valuation +16
#3 Stability +10
#4 Growth +9
Price Setup

Left means cheaper relative valuation. Higher means stronger structure.

Price setup map for ALNY and NTRA Stronger + cheaper Stronger + richer Weaker + cheaper Weaker + richer ALNYNTRA Relative valuation Structural strength

Alnylam Pharmaceuticals, Inc. still looks stronger overall, though current pricing looks more supportive for Natera, Inc..

Valuation position uses peer-relative PE percentile (idx_pct_pe) and peer-relative valuation score where available.

Relative Position vs Comparable Companies
Profitability
On profitability, Alnylam Pharmaceuticals, Inc. ranks near the top of the group; Natera, Inc. sits in the weaker half.
Valuation
Neither side looks especially strong on valuation, though Natera, Inc. still ranks somewhat higher.
Profitability — Dominant Gap
ALNY
78
NTRA
5
Gap+73in favour of ALNY

The profitability lead is mainly driven by a 15.4-point operating margin advantage.

What keeps the gap from being one-sided

Natera, Inc. still shows lower market-fundamental divergence, which keeps the wider picture mixed rather than completely one-sided.

What this means for the comparison

The profitability edge is decisive, even though current pricing and valuation still lean somewhat toward Natera, Inc..

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Break down the ALNY vs NTRA comparison across all dimensions with the full interactive tool.

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Similar profitability-driven comparisons

Explore how ALNY and NTRA each compare against other companies in their peer groups.

Rule-based, descriptive analysis only. Derived from peer percentile dimensions. Not investment advice. Peer groups are determined algorithmically based on structural similarity — not by sector classification alone.

How AssetNext Peer Scores Work

AssetNext scores reflect each company's structural position within its functional peer group — not a ranking against all stocks simultaneously. Peers are identified by similarity across eight financial dimensions, including revenue growth trajectory, margin structure, capital intensity, and earnings stability. A score of 75 means the company ranks in the top quartile within its own peer group, not the entire market.

Four dimension scores drive the overall peer score: Growth (revenue trajectory and expansion dynamics), Quality (margin structure and capital efficiency), Valuation (peer-relative pricing on standard multiples), and Stability (earnings consistency and financial predictability). Each dimension is scored 0–100 relative to the peer group, then combined into an overall peer score using equal weighting.

Scores are recalculated periodically as underlying financial data is updated. All analysis is descriptive and rule-based — AssetNext describes structural realities and never issues buy, sell or hold recommendations.