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Stock Comparison · Structural lead, mixed market

Alnylam Pharmaceuticals vs Natera: Which Stock Looks Stronger in 2026?

Alnylam Pharmaceuticals holds the cleaner structural position, with the lead spread across profitability and valuation. Natera does not offset that deficit through any equally strong structural edge elsewhere. In the market, Natera carries the stronger setup — intact trend against Alnylam Pharmaceuticals's broken trend. That leaves a split case: the structural lead stays with Alnylam Pharmaceuticals, but the market is not currently confirming it.

The comparison is based on similar long-term financial trajectories, not sector labels. Both peer scores are relative to the Russell 1000 universe, making them directly comparable.

Updated 2026-08-16

The clearest score difference appears in profitability. The overall score gap is 23 points in favour of Alnylam Pharmaceuticals, Inc..

Trajectory Similarity
0.75
Similar
Peer-set rank: #2
within Alnylam Pharmaceuticals, Inc.'s functional peer set

This pair is matched through long-term financial trajectory similarity within the selected peer universe.

This level of similarity signals a strong structural match, even though some dimensions still separate the two companies.

The match is driven mainly by investment intensity and revenue growth trajectory.

Similarity drivers
investment intensityrevenue growth trajectory
What reduces the match
margin trend
How to read the score
0.85–1.00 · Very similar0.70–0.84 · Similar0.55–0.69 · Moderately similarbelow 0.55 · Loose match
Peer-Relative Score
ALNY
Alnylam Pharmaceuticals, Inc.
68
Peer-Score
Signal qualitylow
Peer basis: Russell 1000
vs
NTRA
Natera, Inc.
45
Peer-Score
Signal qualitylow
Peer basis: Russell 1000

Scores reflect position relative to comparable companies with similar long-term financial trajectories.

The largest gaps do not all point in the same direction.

Dimension spread: ALNY vs NTRA Profitability 75 23 Stability 64 69 Valuation 57 30 Growth 77 77 ALNY NTRA
Gap Ranking
#1 Profitability +52
#2 Valuation +27
#3 Stability +5
#4 Growth
Price Setup

Left means cheaper relative valuation. Higher means stronger structure.

Price setup map for ALNY and NTRA Stronger + cheaper Stronger + richer Weaker + cheaper Weaker + richer ALNYNTRA Relative valuation Structural strength

Alnylam Pharmaceuticals, Inc. holds the stronger structural profile, but the price setup still leans toward Natera, Inc..

Valuation position uses peer-relative PE percentile (idx_pct_pe) and peer-relative valuation score where available.

Entry today — historical context

Where ALNY and NTRA each sit in their own 5-year price and valuation history.

BASED ON 5-YEAR HISTORY ALNY Neutral · below norm 0th 50th 100th 45 pct gap NTRA Elevated · above norm 0th 50th 100th 54th 99th
Today ALNY sits in the upper-middle of its own 5-year history (54th percentile), while NTRA sits higher in its own history (99th). Within each stock's own 5-year context, ALNY is at a historically more favourable entry position than NTRA. This reflects entry timing, not which company is structurally stronger — peer-relative analysis is a separate question addressed above.

Describes historical entry positioning only. Descriptive — not investment advice.

Relative Position vs Comparable Companies
Profitability
On profitability, Alnylam Pharmaceuticals, Inc. ranks near the top of the group; Natera, Inc. sits in the weaker half.
Valuation
On valuation, Alnylam Pharmaceuticals, Inc. is positioned higher in the group, while Natera, Inc. is closer to the middle.
Profitability — Dominant Gap
ALNY
75
NTRA
23
Gap+52in favour of ALNY

The profitability lead is mainly driven by a 28-point operating margin advantage.

What keeps the gap from being one-sided

On the market side, Natera carries the stronger trend while Alnylam Pharmaceuticals's trend has broken — the market setup does not confirm the structural advantage.

What this means for the comparison

The lead is built on both profitability and valuation, making it broader than a single-dimension result.

Explore full peer positioning in AssetNext

Break down the ALNY vs NTRA comparison across all dimensions with the full interactive tool.

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Similar profitability-driven comparisons

Explore how ALNY and NTRA each compare against other companies in their peer groups.

Rule-based, descriptive analysis only. Derived from peer percentile dimensions. Not investment advice. Peer groups are determined algorithmically based on structural similarity — not by sector classification alone.

How AssetNext Peer Scores Work

AssetNext scores reflect each company's structural position within its functional peer group — not a ranking against all stocks simultaneously. Peers are identified by similarity across eight financial dimensions, including revenue growth trajectory, margin structure, capital intensity, and earnings stability. A score of 75 means the company ranks in the top quartile within its own peer group, not the entire market.

Four dimension scores drive the overall peer score: Growth (revenue trajectory and expansion dynamics), Quality (margin structure and capital efficiency), Valuation (peer-relative pricing on standard multiples), and Stability (earnings consistency and financial predictability). Each dimension is scored 0–100 relative to the peer group, then combined into an overall peer score using equal weighting.

Because scores are peer-relative, the same company can have slightly different scores in different index universes. On comparison pages, both companies are shown within their shared peer universe wherever possible — so the scores are directly comparable. The peer basis is stated on each score card.

Scores are recalculated periodically as underlying financial data is updated. All analysis is descriptive and rule-based — AssetNext describes structural realities and never issues buy, sell or hold recommendations.