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Stock Comparison · Structural lead, mixed market

Affirm Holdings vs Alnylam Pharmaceuticals: Which Stock Looks Stronger in 2026?

Alnylam Pharmaceuticals holds the cleaner structural position, with the lead spread across profitability and stability. Affirm still has the edge on valuation, which keeps the comparison from looking entirely one-sided. Both sides have seen trend damage — neither carries a clear market edge right now. With both trends damaged, the structural comparison carries most of the weight here.

The comparison is based on similar long-term financial trajectories, not sector labels.

Updated 2026-04-05

The clearest separation starts in profitability, but stability adds another real layer to the result. Alnylam Pharmaceuticals, Inc. leads by 24 points on the overall comparison score.

Trajectory Similarity
0.71
Similar
Peer-set rank: #3
within Affirm Holdings, Inc.'s functional peer set

These two companies are linked by measured long-term financial trajectory similarity within the selected peer universe.

The pair sits on a clearly comparable long-term path, though it is not a near-twin match.

The clearest structural overlap shows up in investment intensity and margin trend.

Similarity drivers
investment intensitymargin trend
What reduces the match
revenue growth trajectory
How to read the score
0.85–1.00 · Very similar0.70–0.84 · Similar0.55–0.69 · Moderately similarbelow 0.55 · Loose match
Peer-Relative Score
AFRM
Affirm Holdings, Inc.
32
Peer-Score
Signal qualityMedium
vs
ALNY
Alnylam Pharmaceuticals, Inc.
56
Peer-Score
Signal qualityHigh

Scores reflect position relative to comparable companies with similar long-term financial trajectories.

The largest gaps do not all point in the same direction.

Dimension spread: AFRM vs ALNY Profitability 0 78 Stability 22 53 Valuation 37 14 Growth 81 91 AFRM ALNY
Gap Ranking
#1 Profitability +78
#2 Stability +31
#3 Valuation +23
#4 Growth +10
Price Setup

Left means cheaper relative valuation. Higher means stronger structure.

Price setup map for AFRM and ALNY Stronger + cheaper Stronger + richer Weaker + cheaper Weaker + richer AFRMALNY Relative valuation Structural strength

The price setup looks more supportive for Alnylam Pharmaceuticals, Inc., but Affirm Holdings, Inc. still has the stronger structure.

Valuation position uses peer-relative PE percentile (idx_pct_pe) where available.

Relative Position vs Comparable Companies
Profitability
On profitability, Alnylam Pharmaceuticals, Inc. ranks near the top of the group; Affirm Holdings, Inc. sits in the weaker half.
Stability
Alnylam Pharmaceuticals, Inc. sits in the stronger part of the group on stability, while Affirm Holdings, Inc. is closer to mid-pack.
Profitability — Dominant Gap
AFRM
0
ALNY
78
Gap+78in favour of ALNY

Capital efficiency adds support, with a 62-point ROIC advantage.

What keeps the gap from being one-sided

Absolute pricing still looks more supportive for Affirm, with a forward P/E that is 11.2 turns lower there.

What this means for the comparison

The lead is built on both profitability and stability — though valuation still provides a counterweight.

Explore full peer positioning in AssetNext

Break down the AFRM vs ALNY comparison across all dimensions with the full interactive tool.

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Other comparisons with conflicting dimension signals

Explore how AFRM and ALNY each compare against other companies in their peer groups.

Rule-based, descriptive analysis only. Derived from peer percentile dimensions. Not investment advice. Peer groups are determined algorithmically based on structural similarity — not by sector classification alone.

How AssetNext Peer Scores Work

AssetNext scores reflect each company's structural position within its functional peer group — not a ranking against all stocks simultaneously. Peers are identified by similarity across eight financial dimensions, including revenue growth trajectory, margin structure, capital intensity, and earnings stability. A score of 75 means the company ranks in the top quartile within its own peer group, not the entire market.

Four dimension scores drive the overall peer score: Growth (revenue trajectory and expansion dynamics), Quality (margin structure and capital efficiency), Valuation (peer-relative pricing on standard multiples), and Stability (earnings consistency and financial predictability). Each dimension is scored 0–100 relative to the peer group, then combined into an overall peer score using equal weighting.

Scores are recalculated periodically as underlying financial data is updated. All analysis is descriptive and rule-based — AssetNext describes structural realities and never issues buy, sell or hold recommendations.