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Stock Comparison · Structural lead, mixed market

Affirm Holdings vs Alnylam Pharmaceuticals: Which Stock Looks Stronger in 2026?

Alnylam Pharmaceuticals holds the cleaner structural position, with the lead spread across stability and profitability. Affirm does not offset that deficit through any equally strong structural edge elsewhere. The market setup is currently leaning toward Affirm, which does not confirm the structural lead. That leaves a split case: the structural lead stays with Alnylam Pharmaceuticals, but the market is not currently confirming it.

The comparison is based on similar long-term financial trajectories, not sector labels. Both peer scores are relative to the Russell 1000 universe, making them directly comparable.

Updated 2026-05-17

The clearest separation starts in stability, but profitability adds another real layer to the result. Alnylam Pharmaceuticals, Inc. leads by 20 points on the overall comparison score.

Trajectory Similarity
0.70
Moderately similar
Peer-set rank: #4
within Affirm Holdings, Inc.'s functional peer set

This pair is matched through long-term financial trajectory similarity within the selected peer universe.

The pair shares a valid long-term profile match, but the trajectories are not especially close.

The match is driven mainly by investment intensity and margin trend.

Similarity drivers
investment intensitymargin trend
What reduces the match
revenue growth trajectory
How to read the score
0.85–1.00 · Very similar0.70–0.84 · Similar0.55–0.69 · Moderately similarbelow 0.55 · Loose match
Peer-Relative Score
AFRM
Affirm Holdings, Inc.
44
Peer-Score
Signal qualitylow
Peer basis: Russell 1000
vs
ALNY
Alnylam Pharmaceuticals, Inc.
64
Peer-Score
Signal qualitylow
Peer basis: Russell 1000

Scores reflect position relative to comparable companies with similar long-term financial trajectories.

The largest gaps do not all point in the same direction.

Dimension spread: AFRM vs ALNY Profitability 42 76 Stability 16 65 Valuation 39 31 Growth 82 95 AFRM ALNY
Gap Ranking
#1 Stability +49
#2 Profitability +34
#3 Growth +13
#4 Valuation +8
Price Setup

Left means cheaper relative valuation. Higher means stronger structure.

Price setup map for AFRM and ALNY Stronger + cheaper Stronger + richer Weaker + cheaper Weaker + richer AFRMALNY Relative valuation Structural strength

The setup stays mixed because structure and the price setup do not align cleanly in one direction.

Valuation position uses peer-relative PE percentile (idx_pct_pe) where available.

Entry today — historical context

Where AFRM and ALNY each sit in their own 5-year price and valuation history.

BASED ON 5-YEAR HISTORY AFRM Elevated · near norm 0th 50th 100th 5 pct gap ALNY Elevated · below norm 0th 50th 100th 75th 80th
AFRM (75th percentile) and ALNY (80th percentile) both sit in the upper portion of their own 5-year ranges. The historical entry context is broadly similar for both. This reflects entry timing, not which company is structurally stronger.

Describes historical entry positioning only. Descriptive — not investment advice.

Relative Position vs Comparable Companies
Stability
On stability, Alnylam Pharmaceuticals, Inc. ranks near the top of the group; Affirm Holdings, Inc. sits in the weaker half.
Profitability
On profitability, the edge is clear — both rank well, but Alnylam Pharmaceuticals, Inc. sits noticeably higher.
Stability — Dominant Gap
AFRM
16
ALNY
65
Gap+49in favour of ALNY

The stability gap is very wide, with the stronger side looking materially steadier through time.

What keeps the gap from being one-sided

Absolute pricing still looks more supportive for Affirm, with a forward P/E that is 3.4 turns lower there.

What this means for the comparison

The lead is built on both stability and profitability, making it broader than a single-dimension result.

Explore full peer positioning in AssetNext

Break down the AFRM vs ALNY comparison across all dimensions with the full interactive tool.

Explore full breakdown →
Similar stability-and-profitability comparisons

Explore how AFRM and ALNY each compare against other companies in their peer groups.

Rule-based, descriptive analysis only. Derived from peer percentile dimensions. Not investment advice. Peer groups are determined algorithmically based on structural similarity — not by sector classification alone.

How AssetNext Peer Scores Work

AssetNext scores reflect each company's structural position within its functional peer group — not a ranking against all stocks simultaneously. Peers are identified by similarity across eight financial dimensions, including revenue growth trajectory, margin structure, capital intensity, and earnings stability. A score of 75 means the company ranks in the top quartile within its own peer group, not the entire market.

Four dimension scores drive the overall peer score: Growth (revenue trajectory and expansion dynamics), Quality (margin structure and capital efficiency), Valuation (peer-relative pricing on standard multiples), and Stability (earnings consistency and financial predictability). Each dimension is scored 0–100 relative to the peer group, then combined into an overall peer score using equal weighting.

Because scores are peer-relative, the same company can have slightly different scores in different index universes. On comparison pages, both companies are shown within their shared peer universe wherever possible — so the scores are directly comparable. The peer basis is stated on each score card.

Scores are recalculated periodically as underlying financial data is updated. All analysis is descriptive and rule-based — AssetNext describes structural realities and never issues buy, sell or hold recommendations.